Just like @Clexarews I´d say that regions should already be named when the game launches, not by the players after the launch.
I think this is where the “Location Signals” come into play.
I´d assume that this location signals will be used like private bookmarks and will get put up by players/groups/guilds to be able to navigate on a world.
E.g.
While additional region-naming would not add much to the navigability imo
So I stick to my suggestion that only a few of the most remarkable spots should get a unique name.
Like naming a big square mountain that is covered with orange grass/soil “Lesters Mountain”.