For me I usually will farm most drops from high tier worlds. Regen farming is a great way to get many drops (Regen bombs). There are alot of Regen farms at the TNT network. Main things I will not Regen farm on high tier worlds are soils and mud because drop rate is not worth it, stick with low tier farms for mud and soils also sand.
This is a topic to some Regen farms available through TNT but there are many more.