While I do agree that the Draining compound + Vigor catalyst may have been a bit overpowered, I feel this nerf is taking it a bit to far and pushing the item into uselessness for high end forging.
I feel you only need to do one or the other not both. Either have it add 400 quirk points OR reduce the drain from 5 to 3.
The 400 Quirk points is enough to make most forgers not want to use the item at all, because Quirks and defects are quite bad.
The Debuff being changed from 5 rounds to 3 rounds alone should be enough to break the synergy between both items. However if this nerf and only this nerf alone was done, then the amount of vigor drained per round would need to go up a little bit.
Just one of the two nerfs alone I feel is enough. To make this item not be a consideration anymore for how it was being used. This feels more like a gutting then a nerf.