Get a controller with paddles or an addon for your normal ones, you can then press X on underside of controller while your thumbs are free to do whatever you normally do…
I use Scuf Impact myself…
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This is the addon a friend of mine is very happy with:
https://collectiveminds.ca/shop/playstation/ps4/strikepack-fps-dominator/
I myself use one of these:
It looks like an Xbox controller shell but it has a completely functional PS4 controller inside it with 4 paddles underneath. You can remap the paddles to emulate any clickable button, it has easy replaceable thumb sticks, can extend the R2/L2 and make them like hair triggers, etc., etc.
Those aren’t cheap tho 
But Scuf also has a 2 paddle PS4 controller which looks and is a PS4 controller… They just don’t have the room in that 1 to add 2 more paddles…
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Using a controller for long journeys helps a great deal! But I switch back to mouse and keyboard for anything that requires precision. I’d hate to have to use a controller all the time!